What are mRNA vaccines
How many COVID-19 vaccines are currently being tested
Thus, BioNTech, Pfizer and Moderna are currently leading in the development of a vaccine against COVID-19, but their competitors - such as the Swedish-British pharmaceutical concern AstraZeneca, as well as companies Sanofi, Sinovac and Johnson & Johnson - are likely not will keep themselves waiting for a long time and will present their own developments in the near future.
What are mRNA vaccines
The COVID vaccines are mRNA vaccines, mRNA vaccines are a completely new type of vaccine. Np mRNA vaccine has been licensed for human use before. In essence, we have absolutely no idea what to expect from this vaccine. We have no idea if it will be effective or safe.
Traditional vaccine simply introduce pieces of a virus to stimulate an immune reaction. The new mRNA vaccine is completely different. It actually injects ( transfects) molecules of synthetic genetic material from non-humans sources into our cells. Once in the cells, the genetic material interacts with our transfer RNA (tRNA) to make a foreign protein that supposedly teaches the body to destroy the virus being coded for. Note that these newly created proteins are not regulated by our own DNA, and are thus completely foreign to our cells. What they are fully capable of doing is unknown.
The mRNA molecule is vulnerable to destruction. So, in order to protect the fragile mRNA strands while they are being inserted into our DNA they are coated with PEGylated lipid nanoparticles. This coating hides the mRNA from our immune system which ordinary would kill any foreing material injected into the body. PEGylated lipid nanoparticles have been used in several different drugs for years. Because of their effect on immune system balance, several studies have shown them to introduce allergies and autoimmune diseases. Additionally, PEGylated lipid nanoparticles have been shown to trigger their own immune reactions, and to cause damage to the liver.
* RNA - vaccine (nucleic acid vaccine) - a vaccine whose mechanism of action is based on ribonucleic acid (RNA).
* mRNA - Matrix ribonucleic acid (mRNA, synonym - messenger RNA, mRNA) - RNA containing information about the primary structure (amino acid sequence) of proteins. mRNA is synthesized from DNA during transcription, after which, in turn, is used during translation as a template for protein synthesis.